Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom

Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs and cats that have been increasingly involved in zoonotic trasmission. We isolated and characterized, by WGS, a toxigenic C. ulcera...

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Autores principales: Zendri, Flavia, Isgren, Cajsa Marie, Sinovich, Matthew, Richards-Rios, Peter, Hopkins, Katie L., Russell, Katherine, Groves, Natalie, Litt, David, Fry, Norman K., Timofte, Dorina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203807/
https://www.ncbi.nlm.nih.gov/pubmed/34141732
http://dx.doi.org/10.3389/fvets.2021.650238
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author Zendri, Flavia
Isgren, Cajsa Marie
Sinovich, Matthew
Richards-Rios, Peter
Hopkins, Katie L.
Russell, Katherine
Groves, Natalie
Litt, David
Fry, Norman K.
Timofte, Dorina
author_facet Zendri, Flavia
Isgren, Cajsa Marie
Sinovich, Matthew
Richards-Rios, Peter
Hopkins, Katie L.
Russell, Katherine
Groves, Natalie
Litt, David
Fry, Norman K.
Timofte, Dorina
author_sort Zendri, Flavia
collection PubMed
description Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs and cats that have been increasingly involved in zoonotic trasmission. We isolated and characterized, by WGS, a toxigenic C. ulcerans strain from a diseased horse in the United Kingdom showing clinical signs of respiratory diphtheria comparable to those seen in people. Our results indicate a role for horses as reservoirs for zoonotic C. ulcerans.
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spelling pubmed-82038072021-06-16 Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom Zendri, Flavia Isgren, Cajsa Marie Sinovich, Matthew Richards-Rios, Peter Hopkins, Katie L. Russell, Katherine Groves, Natalie Litt, David Fry, Norman K. Timofte, Dorina Front Vet Sci Veterinary Science Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs and cats that have been increasingly involved in zoonotic trasmission. We isolated and characterized, by WGS, a toxigenic C. ulcerans strain from a diseased horse in the United Kingdom showing clinical signs of respiratory diphtheria comparable to those seen in people. Our results indicate a role for horses as reservoirs for zoonotic C. ulcerans. Frontiers Media S.A. 2021-06-01 /pmc/articles/PMC8203807/ /pubmed/34141732 http://dx.doi.org/10.3389/fvets.2021.650238 Text en Copyright © 2021 Zendri, Isgren, Sinovich, Richards-Rios, Hopkins, Russell, Groves, Litt, Fry and Timofte. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Zendri, Flavia
Isgren, Cajsa Marie
Sinovich, Matthew
Richards-Rios, Peter
Hopkins, Katie L.
Russell, Katherine
Groves, Natalie
Litt, David
Fry, Norman K.
Timofte, Dorina
Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom
title Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom
title_full Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom
title_fullStr Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom
title_full_unstemmed Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom
title_short Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom
title_sort case report: toxigenic corynebacterium ulcerans diphtheria-like infection in a horse in the united kingdom
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203807/
https://www.ncbi.nlm.nih.gov/pubmed/34141732
http://dx.doi.org/10.3389/fvets.2021.650238
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