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Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1

Tripartite motif (TRIM)7 is an E3 ubiquitin ligase that was first identified through its interaction with glycogenin-1 (GN1), the autoglucosyltransferase that initiates glycogen biosynthesis. A growing body of evidence indicates that TRIM7 plays an important role in cancer development, viral pathoge...

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Detalles Bibliográficos
Autores principales:	Muñoz Sosa, Christian J., Issoglio, Federico M., Carrizo, María E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203840/ https://www.ncbi.nlm.nih.gov/pubmed/33989636 http://dx.doi.org/10.1016/j.jbc.2021.100772

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