Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions

OBJECTIVE: Acyl-ghrelin regulates eating, body weight, blood glucose, and GH secretion upon binding to its receptor GHSR (growth hormone secretagogue receptor; ghrelin receptor). GHSR is distributed in several brain regions and some peripheral cell-types including pituitary somatotrophs. The objecti...

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Detalles Bibliográficos
Autores principales: Gupta, Deepali, Patterson, Anna M., Osborne-Lawrence, Sherri, Bookout, Angie L., Varshney, Salil, Shankar, Kripa, Singh, Omprakash, Metzger, Nathan P., Richard, Corine P., Wyler, Steven C., Elmquist, Joel K., Zigman, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203846/
https://www.ncbi.nlm.nih.gov/pubmed/34023483
http://dx.doi.org/10.1016/j.molmet.2021.101258

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