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Rapid assessment of DCLK1 inhibitors using a peptide substrate mobility shift assay
Peptide mobility shift assays provide a sensitive measure of kinase enzymatic activity and can be used to evaluate kinase inhibitors. Herein, we describe a protocol adapted for rapid assessment of doublecortin-like kinase inhibitors. Advantages include rapid iterations of therapeutic compound assess...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203847/ https://www.ncbi.nlm.nih.gov/pubmed/34159321 http://dx.doi.org/10.1016/j.xpro.2021.100587 |