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Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea

Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) c...

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Detalles Bibliográficos
Autores principales: Park, Seon Young, Kim, In Hwang, Yu, Hyun Jin, Paik, Hyoung Rok, Son, Jee Soo, Kim, Ji Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Animal Sciences and Technology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203990/
https://www.ncbi.nlm.nih.gov/pubmed/34189513
http://dx.doi.org/10.5187/jast.2021.e47
Descripción
Sumario:Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor (epf)(−)/ muraminidase-released protein (mrp)(+)/ suilysin (sly)(−) S. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea.