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Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea

Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) c...

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Autores principales: Park, Seon Young, Kim, In Hwang, Yu, Hyun Jin, Paik, Hyoung Rok, Son, Jee Soo, Kim, Ji Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Animal Sciences and Technology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203990/
https://www.ncbi.nlm.nih.gov/pubmed/34189513
http://dx.doi.org/10.5187/jast.2021.e47
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author Park, Seon Young
Kim, In Hwang
Yu, Hyun Jin
Paik, Hyoung Rok
Son, Jee Soo
Kim, Ji Hyung
author_facet Park, Seon Young
Kim, In Hwang
Yu, Hyun Jin
Paik, Hyoung Rok
Son, Jee Soo
Kim, Ji Hyung
author_sort Park, Seon Young
collection PubMed
description Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor (epf)(−)/ muraminidase-released protein (mrp)(+)/ suilysin (sly)(−) S. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea.
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spelling pubmed-82039902021-06-28 Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea Park, Seon Young Kim, In Hwang Yu, Hyun Jin Paik, Hyoung Rok Son, Jee Soo Kim, Ji Hyung J Anim Sci Technol Research Article Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor (epf)(−)/ muraminidase-released protein (mrp)(+)/ suilysin (sly)(−) S. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea. Korean Society of Animal Sciences and Technology 2021-05 2021-05-31 /pmc/articles/PMC8203990/ /pubmed/34189513 http://dx.doi.org/10.5187/jast.2021.e47 Text en © Copyright 2021 Korean Society of Animal Science and Technology https://creativecommons.org/licenses/by-nc/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Park, Seon Young
Kim, In Hwang
Yu, Hyun Jin
Paik, Hyoung Rok
Son, Jee Soo
Kim, Ji Hyung
Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
title Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
title_full Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
title_fullStr Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
title_full_unstemmed Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
title_short Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
title_sort complete genome sequence of serotype 3 streptococcus suis int-01, isolated from a domestic pig in korea
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203990/
https://www.ncbi.nlm.nih.gov/pubmed/34189513
http://dx.doi.org/10.5187/jast.2021.e47
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