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Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea
Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Animal Sciences and Technology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203990/ https://www.ncbi.nlm.nih.gov/pubmed/34189513 http://dx.doi.org/10.5187/jast.2021.e47 |
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author | Park, Seon Young Kim, In Hwang Yu, Hyun Jin Paik, Hyoung Rok Son, Jee Soo Kim, Ji Hyung |
author_facet | Park, Seon Young Kim, In Hwang Yu, Hyun Jin Paik, Hyoung Rok Son, Jee Soo Kim, Ji Hyung |
author_sort | Park, Seon Young |
collection | PubMed |
description | Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor (epf)(−)/ muraminidase-released protein (mrp)(+)/ suilysin (sly)(−) S. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea. |
format | Online Article Text |
id | pubmed-8203990 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Animal Sciences and Technology |
record_format | MEDLINE/PubMed |
spelling | pubmed-82039902021-06-28 Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea Park, Seon Young Kim, In Hwang Yu, Hyun Jin Paik, Hyoung Rok Son, Jee Soo Kim, Ji Hyung J Anim Sci Technol Research Article Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor (epf)(−)/ muraminidase-released protein (mrp)(+)/ suilysin (sly)(−) S. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea. Korean Society of Animal Sciences and Technology 2021-05 2021-05-31 /pmc/articles/PMC8203990/ /pubmed/34189513 http://dx.doi.org/10.5187/jast.2021.e47 Text en © Copyright 2021 Korean Society of Animal Science and Technology https://creativecommons.org/licenses/by-nc/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Park, Seon Young Kim, In Hwang Yu, Hyun Jin Paik, Hyoung Rok Son, Jee Soo Kim, Ji Hyung Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea |
title | Complete genome sequence of serotype 3 Streptococcus
suis INT-01, isolated from a domestic pig in Korea |
title_full | Complete genome sequence of serotype 3 Streptococcus
suis INT-01, isolated from a domestic pig in Korea |
title_fullStr | Complete genome sequence of serotype 3 Streptococcus
suis INT-01, isolated from a domestic pig in Korea |
title_full_unstemmed | Complete genome sequence of serotype 3 Streptococcus
suis INT-01, isolated from a domestic pig in Korea |
title_short | Complete genome sequence of serotype 3 Streptococcus
suis INT-01, isolated from a domestic pig in Korea |
title_sort | complete genome sequence of serotype 3 streptococcus
suis int-01, isolated from a domestic pig in korea |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203990/ https://www.ncbi.nlm.nih.gov/pubmed/34189513 http://dx.doi.org/10.5187/jast.2021.e47 |
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