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Effects of recovery from short-term heat stress exposure on feed intake, plasma amino acid profiles, and metabolites in growing pigs
Heat stress (HS) damages health and decreases performance variables in pigs, and if severe enough, causes mortality. However, metabolic changes under HS and recovery following HS are poorly understood. Therefore, this study was aimed to expose the essential mechanisms by which growing pigs respond t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Animal Sciences and Technology
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204004/ https://www.ncbi.nlm.nih.gov/pubmed/34189503 http://dx.doi.org/10.5187/jast.2021.e53 |
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author | Kim, Byeonghyeon Reddy, Kondreddy Eswar Kim, Hye Ran Kim, Ki Hyun Lee, Yookyung Kim, Minji Ji, Sang Yun Lee, Sung Dae Jeong, Jin Young |
author_facet | Kim, Byeonghyeon Reddy, Kondreddy Eswar Kim, Hye Ran Kim, Ki Hyun Lee, Yookyung Kim, Minji Ji, Sang Yun Lee, Sung Dae Jeong, Jin Young |
author_sort | Kim, Byeonghyeon |
collection | PubMed |
description | Heat stress (HS) damages health and decreases performance variables in pigs, and if severe enough, causes mortality. However, metabolic changes under HS and recovery following HS are poorly understood. Therefore, this study was aimed to expose the essential mechanisms by which growing pigs respond to HS and the temporal pattern of plasma concentrations (PC) of amino acids (AAs) and metabolites. Crossbred male growing pigs were penned separately and allowed to adapt to thermal-neutral (TN) conditions (20°C and 80% relative humidity; TN[-1D]). On the first day, all pigs were exposed to HS for 24 h (36°C and 60% relative humidity), then to TN conditions for 5 days (TN[2D] to TN[5D]). All pigs had ad libitum access to water and 3 kg feed twice daily. Rectal temperature (RT) and feed intake (FI) were determined daily. HS pigs had higher RT (40.72°C) and lower (50%) FI than TN(-1D) pigs (p < 0.01). The PC of indispensable (threonine, valine, and methionine) and dispensable (cysteine and tyrosine) AAs were higher (p < 0.05) in HS than TN(-1D) pigs and remained increased during recovery time. Nonprotein α-aminobutyric acid and β-alanine concentrations were higher (p < 0.05) in HS than TN(-1D) pigs. The metabolite concentration of creatinine was higher (p < 0.01) under HS treatment than other treatments, but that of alanine and leucine remained increased (p < 0.05) through 5 d of recovery. In summary, some major differences were found in plasma AA profiles and metabolites between HS- and TN-condition pigs. This indicates that the HS pigs were forced to alter their metabolism, and these results provide information about mechanisms of acute HS responses relative to the recovery time. |
format | Online Article Text |
id | pubmed-8204004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Animal Sciences and Technology |
record_format | MEDLINE/PubMed |
spelling | pubmed-82040042021-06-28 Effects of recovery from short-term heat stress exposure on feed intake, plasma amino acid profiles, and metabolites in growing pigs Kim, Byeonghyeon Reddy, Kondreddy Eswar Kim, Hye Ran Kim, Ki Hyun Lee, Yookyung Kim, Minji Ji, Sang Yun Lee, Sung Dae Jeong, Jin Young J Anim Sci Technol Research Article Heat stress (HS) damages health and decreases performance variables in pigs, and if severe enough, causes mortality. However, metabolic changes under HS and recovery following HS are poorly understood. Therefore, this study was aimed to expose the essential mechanisms by which growing pigs respond to HS and the temporal pattern of plasma concentrations (PC) of amino acids (AAs) and metabolites. Crossbred male growing pigs were penned separately and allowed to adapt to thermal-neutral (TN) conditions (20°C and 80% relative humidity; TN[-1D]). On the first day, all pigs were exposed to HS for 24 h (36°C and 60% relative humidity), then to TN conditions for 5 days (TN[2D] to TN[5D]). All pigs had ad libitum access to water and 3 kg feed twice daily. Rectal temperature (RT) and feed intake (FI) were determined daily. HS pigs had higher RT (40.72°C) and lower (50%) FI than TN(-1D) pigs (p < 0.01). The PC of indispensable (threonine, valine, and methionine) and dispensable (cysteine and tyrosine) AAs were higher (p < 0.05) in HS than TN(-1D) pigs and remained increased during recovery time. Nonprotein α-aminobutyric acid and β-alanine concentrations were higher (p < 0.05) in HS than TN(-1D) pigs. The metabolite concentration of creatinine was higher (p < 0.01) under HS treatment than other treatments, but that of alanine and leucine remained increased (p < 0.05) through 5 d of recovery. In summary, some major differences were found in plasma AA profiles and metabolites between HS- and TN-condition pigs. This indicates that the HS pigs were forced to alter their metabolism, and these results provide information about mechanisms of acute HS responses relative to the recovery time. Korean Society of Animal Sciences and Technology 2021-05 2021-05-31 /pmc/articles/PMC8204004/ /pubmed/34189503 http://dx.doi.org/10.5187/jast.2021.e53 Text en © Copyright 2021 Korean Society of Animal Sciences and Technology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Kim, Byeonghyeon Reddy, Kondreddy Eswar Kim, Hye Ran Kim, Ki Hyun Lee, Yookyung Kim, Minji Ji, Sang Yun Lee, Sung Dae Jeong, Jin Young Effects of recovery from short-term heat stress exposure on feed intake, plasma amino acid profiles, and metabolites in growing pigs |
title | Effects of recovery from short-term heat stress exposure on feed
intake, plasma amino acid profiles, and metabolites in growing
pigs |
title_full | Effects of recovery from short-term heat stress exposure on feed
intake, plasma amino acid profiles, and metabolites in growing
pigs |
title_fullStr | Effects of recovery from short-term heat stress exposure on feed
intake, plasma amino acid profiles, and metabolites in growing
pigs |
title_full_unstemmed | Effects of recovery from short-term heat stress exposure on feed
intake, plasma amino acid profiles, and metabolites in growing
pigs |
title_short | Effects of recovery from short-term heat stress exposure on feed
intake, plasma amino acid profiles, and metabolites in growing
pigs |
title_sort | effects of recovery from short-term heat stress exposure on feed
intake, plasma amino acid profiles, and metabolites in growing
pigs |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204004/ https://www.ncbi.nlm.nih.gov/pubmed/34189503 http://dx.doi.org/10.5187/jast.2021.e53 |
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