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Shear Stress Accumulation Enhances von Willebrand Factor-Induced Platelet P-Selectin Translocation in a PI3K/Akt Pathway-Dependent Manner

Platelet adhesion and activation through the interaction of von Willebrand factor (VWF) with platelet glycoprotein (GP) Ibα are the early key events in hemostasis and thrombosis especially under high blood shear stress. P-selectin translocation from α granule to the cell surface is a typical platele...

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Detalles Bibliográficos
Autores principales:	Fang, Jinhua, Sun, Xiaoxi, Liu, Silu, Yang, Pu, Lin, Jiangguo, Feng, Jingjing, Cruz, Miguel A., Dong, Jing-fei, Fang, Ying, Wu, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204100/ https://www.ncbi.nlm.nih.gov/pubmed/34141704 http://dx.doi.org/10.3389/fcell.2021.642108

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