Cargando…
Inhibition of Influenza Virus Polymerase by Interfering with Its Protein–Protein Interactions
[Image: see text] Influenza (flu) virus is a serious threat to global health with the potential to generate devastating pandemics. The availability of broad spectrum antiviral drugs is an unequaled weapon during pandemic events, especially when a vaccine is still not available. One of the most promi...
Autores principales: | Massari, Serena, Desantis, Jenny, Nizi, Maria Giulia, Cecchetti, Violetta, Tabarrini, Oriana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204303/ https://www.ncbi.nlm.nih.gov/pubmed/33044059 http://dx.doi.org/10.1021/acsinfecdis.0c00552 |
Ejemplares similares
-
Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase
por: Massari, Serena, et al.
Publicado: (2021) -
1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity
por: Desantis, Jenny, et al.
Publicado: (2020) -
Privileged Scaffolds for Potent and Specific Inhibitors of Mono-ADP-Ribosylating PARPs
por: Nizi, Maria Giulia, et al.
Publicado: (2023) -
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors
por: Massari, Serena, et al.
Publicado: (2018) -
Medicinal Chemistry
Perspective on Targeting Mono-ADP-Ribosylating
PARPs with Small Molecules
por: Nizi, Maria Giulia, et al.
Publicado: (2022)