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Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify between-group differences in DNA methylation

BACKGROUND: The combination of sodium bisulfite treatment with highly-parallel sequencing is a common method for quantifying DNA methylation across the genome. The power to detect between-group differences in DNA methylation using bisulfite-sequencing approaches is influenced by both experimental (e...

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Detalles Bibliográficos
Autores principales:	Seiler Vellame, Dorothea, Castanho, Isabel, Dahir, Aisha, Mill, Jonathan, Hannon, Eilis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204428/ https://www.ncbi.nlm.nih.gov/pubmed/34126923 http://dx.doi.org/10.1186/s12864-021-07721-z

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