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Exploration and validation of hub genes and pathways in the progression of hypoplastic left heart syndrome via weighted gene co-expression network analysis

BACKGROUND: Despite significant progress in surgical treatment of hypoplastic left heart syndrome (HLHS), its mortality and morbidity are still high. Little is known about the molecular abnormalities of the syndrome. In this study, we aimed to probe into hub genes and key pathways in the progression...

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Detalles Bibliográficos
Autores principales: Liu, Xuelan, Shang, Honglei, Li, Bin, Zhao, Liyun, Hua, Ying, Wu, Kaiyuan, Hu, Manman, Fan, Taibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204459/
https://www.ncbi.nlm.nih.gov/pubmed/34130651
http://dx.doi.org/10.1186/s12872-021-02108-0

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