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Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

As a key process within the tissue microenvironment, integrin signaling can influence cell functional responses to growth factor stimuli. We show here that clustering of integrin α5ß1 at the plasma membrane of colorectal cancer-derived epithelial cells modulates their ability to respond to stimulati...

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Detalles Bibliográficos
Autores principales:	Starchenko, Alina, Graves-Deal, Ramona, Brubaker, Douglas, Li, Cunxi, Yang, Yuping, Singh, Bhuminder, Coffey, Robert J, Lauffenburger, Douglas A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204629/ https://www.ncbi.nlm.nih.gov/pubmed/34037774 http://dx.doi.org/10.1093/intbio/zyab009

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