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Cardiovascular Risk in Rheumatoid Arthritis: Literature Review
Rheumatoid arthritis (RA) is the most common inflammatory arthritis disease with a worldwide prevalence of 1–3%. RA patients are at higher risk of atherosclerosis than their matched age-sex controls. Cardiovascular diseases (CVDs) account for a 50% risk of increased mortality and morbidity in RA. Th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OMJ
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204633/ https://www.ncbi.nlm.nih.gov/pubmed/34164156 http://dx.doi.org/10.5001/omj.2021.25 |
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author | Hannawi, Suad MA Hannawi, Haifa Al Salmi, Issa |
author_facet | Hannawi, Suad MA Hannawi, Haifa Al Salmi, Issa |
author_sort | Hannawi, Suad MA |
collection | PubMed |
description | Rheumatoid arthritis (RA) is the most common inflammatory arthritis disease with a worldwide prevalence of 1–3%. RA patients are at higher risk of atherosclerosis than their matched age-sex controls. Cardiovascular diseases (CVDs) account for a 50% risk of increased mortality and morbidity in RA. The pattern of CVD in RA patients differs from that in the general population; RA patients are more likely to have silent ischemic heart disease, sudden death, heart failure, and die early. RA patients tend to have a 5–10 years reduction in their life span than their matched healthy population. Traditional (classical) CV risk factors work separately or synergistically with the underlying inflammation to increase CVD risk in RA. Moreover, inflammation is defined as an independent CVD risk factor. This literature review aims to discuss the traditional CVD risk factors and their association with inflammation in RA. |
format | Online Article Text |
id | pubmed-8204633 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | OMJ |
record_format | MEDLINE/PubMed |
spelling | pubmed-82046332021-06-22 Cardiovascular Risk in Rheumatoid Arthritis: Literature Review Hannawi, Suad MA Hannawi, Haifa Al Salmi, Issa Oman Med J Review Article Rheumatoid arthritis (RA) is the most common inflammatory arthritis disease with a worldwide prevalence of 1–3%. RA patients are at higher risk of atherosclerosis than their matched age-sex controls. Cardiovascular diseases (CVDs) account for a 50% risk of increased mortality and morbidity in RA. The pattern of CVD in RA patients differs from that in the general population; RA patients are more likely to have silent ischemic heart disease, sudden death, heart failure, and die early. RA patients tend to have a 5–10 years reduction in their life span than their matched healthy population. Traditional (classical) CV risk factors work separately or synergistically with the underlying inflammation to increase CVD risk in RA. Moreover, inflammation is defined as an independent CVD risk factor. This literature review aims to discuss the traditional CVD risk factors and their association with inflammation in RA. OMJ 2021-05-31 /pmc/articles/PMC8204633/ /pubmed/34164156 http://dx.doi.org/10.5001/omj.2021.25 Text en The OMJ is Published Bimonthly and Copyrighted 2021 by the OMSB. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC) 4.0 License. http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Review Article Hannawi, Suad MA Hannawi, Haifa Al Salmi, Issa Cardiovascular Risk in Rheumatoid Arthritis: Literature Review |
title | Cardiovascular Risk in Rheumatoid Arthritis: Literature Review |
title_full | Cardiovascular Risk in Rheumatoid Arthritis: Literature Review |
title_fullStr | Cardiovascular Risk in Rheumatoid Arthritis: Literature Review |
title_full_unstemmed | Cardiovascular Risk in Rheumatoid Arthritis: Literature Review |
title_short | Cardiovascular Risk in Rheumatoid Arthritis: Literature Review |
title_sort | cardiovascular risk in rheumatoid arthritis: literature review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204633/ https://www.ncbi.nlm.nih.gov/pubmed/34164156 http://dx.doi.org/10.5001/omj.2021.25 |
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