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ArfGAP1 inhibits mTORC1 lysosomal localization and activation

The mammalian target of rapamycin complex 1 (mTORC1) integrates nutrients, growth factors, stress, and energy status to regulate cell growth and metabolism. Amino acids promote mTORC1 lysosomal localization and subsequent activation. However, the subcellular location or interacting proteins of mTORC...

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Detalles Bibliográficos
Autores principales:	Meng, Delong, Yang, Qianmei, Melick, Chase H, Park, Brenden C, Hsieh, Ting‐Sung, Curukovic, Adna, Jeong, Mi‐Hyeon, Zhang, Junmei, James, Nicholas G, Jewell, Jenna L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204869/ https://www.ncbi.nlm.nih.gov/pubmed/33988249 http://dx.doi.org/10.15252/embj.2020106412

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