Selection of established tumour cells through narrow diameter micropores enriches for elevated Ras/Raf/MEK/ERK MAPK signalling and enhanced tumour growth

As normal cells become cancer cells, and progress towards malignancy, they become progressively softer. Advantages of this change are that tumour cells become more deformable, and better able to move through narrow constraints. We designed a positive selection strategy that enriched for cells which...

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Detalles Bibliográficos
Autores principales: Rudzka, Dominika a, Mason, Susan, Neilson, Matthew, McGarry, Lynn, Kalna, Gabriela, Hedley, Ann, Blyth, Karen, Olson, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204978/
https://www.ncbi.nlm.nih.gov/pubmed/32569510
http://dx.doi.org/10.1080/21541248.2020.1780108

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