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An efficient enzyme-triggered controlled release system for colon-targeted oral delivery to combat dextran sodium sulfate (DSS)-induced colitis in mice

Oral route colon-targeted drug delivery systems (CDDSs) are desirable for the treatment of ulcerative colitis (UC). However, CDDSs are challenging owing to the physiological and anatomical barriers associated with the gastrointestinal tract (GIT). In this study, we developed an effective enzyme-trig...

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Detalles Bibliográficos
Autores principales: Li, Shangyong, Jin, Mengfei, Wu, Yanhong, Jung, Samil, Li, Dandan, He, Ningning, Lee, Myeong-sok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205034/
https://www.ncbi.nlm.nih.gov/pubmed/34121560
http://dx.doi.org/10.1080/10717544.2021.1934189