Of mitochondrion and COVID-19

COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more...

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Detalles Bibliográficos
Autores principales: Alfarouk, Khalid Omer, Alhoufie, Sari T. S., Hifny, Abdelhameed, Schwartz, Laurent, Alqahtani, Ali S., Ahmed, Samrein B. M., Alqahtani, Ali M., Alqahtani, Saad S., Muddathir, Abdel Khalig, Ali, Heyam, Bashir, Adil H. H., Ibrahim, Muntaser E., Greco, Maria Raffaella, Cardone, Rosa A., Harguindey, Salvador, Reshkin, Stephan Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205080/
https://www.ncbi.nlm.nih.gov/pubmed/34107824
http://dx.doi.org/10.1080/14756366.2021.1937144
Descripción
Sumario:COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19’s signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19.

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