Of mitochondrion and COVID-19

COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more...

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Autores principales: Alfarouk, Khalid Omer, Alhoufie, Sari T. S., Hifny, Abdelhameed, Schwartz, Laurent, Alqahtani, Ali S., Ahmed, Samrein B. M., Alqahtani, Ali M., Alqahtani, Saad S., Muddathir, Abdel Khalig, Ali, Heyam, Bashir, Adil H. H., Ibrahim, Muntaser E., Greco, Maria Raffaella, Cardone, Rosa A., Harguindey, Salvador, Reshkin, Stephan Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205080/
https://www.ncbi.nlm.nih.gov/pubmed/34107824
http://dx.doi.org/10.1080/14756366.2021.1937144
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author Alfarouk, Khalid Omer
Alhoufie, Sari T. S.
Hifny, Abdelhameed
Schwartz, Laurent
Alqahtani, Ali S.
Ahmed, Samrein B. M.
Alqahtani, Ali M.
Alqahtani, Saad S.
Muddathir, Abdel Khalig
Ali, Heyam
Bashir, Adil H. H.
Ibrahim, Muntaser E.
Greco, Maria Raffaella
Cardone, Rosa A.
Harguindey, Salvador
Reshkin, Stephan Joel
author_facet Alfarouk, Khalid Omer
Alhoufie, Sari T. S.
Hifny, Abdelhameed
Schwartz, Laurent
Alqahtani, Ali S.
Ahmed, Samrein B. M.
Alqahtani, Ali M.
Alqahtani, Saad S.
Muddathir, Abdel Khalig
Ali, Heyam
Bashir, Adil H. H.
Ibrahim, Muntaser E.
Greco, Maria Raffaella
Cardone, Rosa A.
Harguindey, Salvador
Reshkin, Stephan Joel
author_sort Alfarouk, Khalid Omer
collection PubMed
description COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19’s signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19.
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spelling pubmed-82050802021-06-24 Of mitochondrion and COVID-19 Alfarouk, Khalid Omer Alhoufie, Sari T. S. Hifny, Abdelhameed Schwartz, Laurent Alqahtani, Ali S. Ahmed, Samrein B. M. Alqahtani, Ali M. Alqahtani, Saad S. Muddathir, Abdel Khalig Ali, Heyam Bashir, Adil H. H. Ibrahim, Muntaser E. Greco, Maria Raffaella Cardone, Rosa A. Harguindey, Salvador Reshkin, Stephan Joel J Enzyme Inhib Med Chem Review Article COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19’s signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19. Taylor & Francis 2021-06-09 /pmc/articles/PMC8205080/ /pubmed/34107824 http://dx.doi.org/10.1080/14756366.2021.1937144 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Alfarouk, Khalid Omer
Alhoufie, Sari T. S.
Hifny, Abdelhameed
Schwartz, Laurent
Alqahtani, Ali S.
Ahmed, Samrein B. M.
Alqahtani, Ali M.
Alqahtani, Saad S.
Muddathir, Abdel Khalig
Ali, Heyam
Bashir, Adil H. H.
Ibrahim, Muntaser E.
Greco, Maria Raffaella
Cardone, Rosa A.
Harguindey, Salvador
Reshkin, Stephan Joel
Of mitochondrion and COVID-19
title Of mitochondrion and COVID-19
title_full Of mitochondrion and COVID-19
title_fullStr Of mitochondrion and COVID-19
title_full_unstemmed Of mitochondrion and COVID-19
title_short Of mitochondrion and COVID-19
title_sort of mitochondrion and covid-19
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205080/
https://www.ncbi.nlm.nih.gov/pubmed/34107824
http://dx.doi.org/10.1080/14756366.2021.1937144
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