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Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor
Disorders of lysosomal physiology have increasingly been found to underlie the pathology of a rapidly growing cast of neurodevelopmental disorders and sporadic diseases of aging. One cardinal aspect of lysosomal (dys)function is lysosomal acidification in which defects trigger lysosomal stress signa...
Autores principales: | Ponsford, Amy H., Ryan, Thomas A., Raimondi, Andrea, Cocucci, Emanuele, Wycislo, Susanne A., Fröhlich, Florian, Swan, Laura E., Stagi, Massimiliano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205096/ https://www.ncbi.nlm.nih.gov/pubmed/32515674 http://dx.doi.org/10.1080/15548627.2020.1771858 |
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