Pyronaridine–artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study

BACKGROUND: In Phase II/III randomized controlled clinical trials for the treatment of acute uncomplicated malaria, pyronaridine–artesunate demonstrated high efficacy and a safety profile consistent with that of comparators, except that asymptomatic, mainly mild-to-moderate transient increases in li...

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Detalles Bibliográficos
Autores principales: Tona Lutete, Gaston, Mombo-Ngoma, Ghyslain, Assi, Serge-Brice, Bigoga, Jude D., Koukouikila-Koussounda, Felix, Ntamabyaliro, Nsengi Y., Ntoumi, Francine, Agnandji, Selidji T., Groger, Mirjam, Shin, Jangsik, Borghini-Fuhrer, Isabelle, Arbe-Barnes, Sarah, Allen, Stephen J., Kremsner, Peter G., Miller, Robert, Duparc, Stephan, Ramharter, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205155/
https://www.ncbi.nlm.nih.gov/pubmed/34129601
http://dx.doi.org/10.1371/journal.pmed.1003669

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