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SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These mutations can affect viral properties such as infectivity and immune resistance. Although the sensitivity of naturally occurring SARS-CoV-2 variants to humoral immunity has been investigated, sensitivity to human leukocyt...

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Detalles Bibliográficos
Autores principales: Motozono, Chihiro, Toyoda, Mako, Zahradnik, Jiri, Saito, Akatsuki, Nasser, Hesham, Tan, Toong Seng, Ngare, Isaac, Kimura, Izumi, Uriu, Keiya, Kosugi, Yusuke, Yue, Yuan, Shimizu, Ryo, Ito, Jumpei, Torii, Shiho, Yonekawa, Akiko, Shimono, Nobuyuki, Nagasaki, Yoji, Minami, Rumi, Toya, Takashi, Sekiya, Noritaka, Fukuhara, Takasuke, Matsuura, Yoshiharu, Schreiber, Gideon, Ikeda, Terumasa, Nakagawa, So, Ueno, Takamasa, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205251/
https://www.ncbi.nlm.nih.gov/pubmed/34171266
http://dx.doi.org/10.1016/j.chom.2021.06.006