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The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study

BACKGROUND: The aim of this study was to evaluate the risk factors for hospitalizations of cases with positive and negative COVID-19 tests. METHODS: In this case-control study, the case and control groups consisted of 292 COVID-19 patients and 296 non-COVID-19 patients. Patients who referred to a re...

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Autores principales: Ghanei, Mostafa, Keyvani, Hossein, Haghdoost, Aliakbar, Abolghasemi, Hassan, Janbabaei, Ghasem, Reza Jamshidi, Hamdi, Hosein Ghazale, Amir, Hassan Saadat, Seyed, Gholami Fesharaki, Mohammad, Raei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205271/
https://www.ncbi.nlm.nih.gov/pubmed/34186280
http://dx.doi.org/10.1016/j.intimp.2021.107894
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author Ghanei, Mostafa
Keyvani, Hossein
Haghdoost, Aliakbar
Abolghasemi, Hassan
Janbabaei, Ghasem
Reza Jamshidi, Hamdi
Hosein Ghazale, Amir
Hassan Saadat, Seyed
Gholami Fesharaki, Mohammad
Raei, Mehdi
author_facet Ghanei, Mostafa
Keyvani, Hossein
Haghdoost, Aliakbar
Abolghasemi, Hassan
Janbabaei, Ghasem
Reza Jamshidi, Hamdi
Hosein Ghazale, Amir
Hassan Saadat, Seyed
Gholami Fesharaki, Mohammad
Raei, Mehdi
author_sort Ghanei, Mostafa
collection PubMed
description BACKGROUND: The aim of this study was to evaluate the risk factors for hospitalizations of cases with positive and negative COVID-19 tests. METHODS: In this case-control study, the case and control groups consisted of 292 COVID-19 patients and 296 non-COVID-19 patients. Patients who referred to a reference laboratory in Tehran (Iran) in March 2020 were selected and interviewed. The patients were contacted by telephone and data were recorded through a questionnaire. RESULTS: The sample of this study consisted of 588 patients (349 [59%] females, 239 [41%] males) with a mean age of 42 ± 15. The results of this study showed that comorbidities like diabetes (OR = 7.42), hypertension (OR = 4.85), asthma and respiratory diseases (OR = 5.64) in addition to symptoms including fever (OR = 6.67), chills (OR = 11.2), anorexia (OR = 11.3), dyspnea (OR = 4.8), weakness and lethargy (OR = 5.7) were the most predictive variables for hospitalization of non-COVID-19 cases. Furthermore, demographical variables like male gender (OR = 3.71), high age (>50; OR = 3.12), BMI (>25; OR = 2.37), travel (OR = 2.79), comorbidities including diabetes (OR = 5.26), hypertension (OR = 3.7) and underlying immunosuppressant patients receiving corticosteroid therapy (OR = 3.62) in addition to symptoms like anorexia [OR = 2.55] and dyspnea (OR = 6.99) tend to increase the risk of hospital admission in COVID-19 patients, suggesting their predictive values for hospitalization of COVID-19 patients. CONCLUSION: Our results indicated that different factors tend to increase the odds of hospital admission in patients with positive and negative COVID-19 tests, suggesting their predictive values for hospitalization.
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spelling pubmed-82052712021-06-16 The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study Ghanei, Mostafa Keyvani, Hossein Haghdoost, Aliakbar Abolghasemi, Hassan Janbabaei, Ghasem Reza Jamshidi, Hamdi Hosein Ghazale, Amir Hassan Saadat, Seyed Gholami Fesharaki, Mohammad Raei, Mehdi Int Immunopharmacol Article BACKGROUND: The aim of this study was to evaluate the risk factors for hospitalizations of cases with positive and negative COVID-19 tests. METHODS: In this case-control study, the case and control groups consisted of 292 COVID-19 patients and 296 non-COVID-19 patients. Patients who referred to a reference laboratory in Tehran (Iran) in March 2020 were selected and interviewed. The patients were contacted by telephone and data were recorded through a questionnaire. RESULTS: The sample of this study consisted of 588 patients (349 [59%] females, 239 [41%] males) with a mean age of 42 ± 15. The results of this study showed that comorbidities like diabetes (OR = 7.42), hypertension (OR = 4.85), asthma and respiratory diseases (OR = 5.64) in addition to symptoms including fever (OR = 6.67), chills (OR = 11.2), anorexia (OR = 11.3), dyspnea (OR = 4.8), weakness and lethargy (OR = 5.7) were the most predictive variables for hospitalization of non-COVID-19 cases. Furthermore, demographical variables like male gender (OR = 3.71), high age (>50; OR = 3.12), BMI (>25; OR = 2.37), travel (OR = 2.79), comorbidities including diabetes (OR = 5.26), hypertension (OR = 3.7) and underlying immunosuppressant patients receiving corticosteroid therapy (OR = 3.62) in addition to symptoms like anorexia [OR = 2.55] and dyspnea (OR = 6.99) tend to increase the risk of hospital admission in COVID-19 patients, suggesting their predictive values for hospitalization of COVID-19 patients. CONCLUSION: Our results indicated that different factors tend to increase the odds of hospital admission in patients with positive and negative COVID-19 tests, suggesting their predictive values for hospitalization. Published by Elsevier B.V. 2021-09 2021-06-15 /pmc/articles/PMC8205271/ /pubmed/34186280 http://dx.doi.org/10.1016/j.intimp.2021.107894 Text en © 2021 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Ghanei, Mostafa
Keyvani, Hossein
Haghdoost, Aliakbar
Abolghasemi, Hassan
Janbabaei, Ghasem
Reza Jamshidi, Hamdi
Hosein Ghazale, Amir
Hassan Saadat, Seyed
Gholami Fesharaki, Mohammad
Raei, Mehdi
The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study
title The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study
title_full The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study
title_fullStr The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study
title_full_unstemmed The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study
title_short The risk factors and related hospitalizations for cases with positive and negative COVID-19 tests: A case-control study
title_sort risk factors and related hospitalizations for cases with positive and negative covid-19 tests: a case-control study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205271/
https://www.ncbi.nlm.nih.gov/pubmed/34186280
http://dx.doi.org/10.1016/j.intimp.2021.107894
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