Cargando…

Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients: results from a prospective observational study

OBJECTIVES: Dexamethasone has become the standard of care for severe coronavirus disease 2019 (COVID-19), but its virological impact is poorly understood. The objectives of this work were to characterize the kinetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) concentration in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mühlemann, Barbara, Thibeault, Charlotte, Hillus, David, Helbig, Elisa T., Lippert, Lena J., Tober-Lau, Pinkus, Schwarz, Tatjana, Müller, Marcel A., Witzenrath, Martin, Suttorp, Norbert, Sander, Leif E., Drosten, Christian, Jones, Terry C., Corman, Victor M., Kurth, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases. 2021
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205283/ https://www.ncbi.nlm.nih.gov/pubmed/34139335 http://dx.doi.org/10.1016/j.cmi.2021.06.008

Ejemplares similares

Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
por: Tober-Lau, Pinkus, et al.
Publicado: (2021)

Long-term immunogenicity of BNT162b2 vaccination in older people and younger health-care workers
por: Tober-Lau, Pinkus, et al.
Publicado: (2021)

Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study
por: Lingscheid, Tilman, et al.
Publicado: (2022)

Short- and long-term T cell and antibody responses following dexamethasone treatment in COVID-19
por: Thibeault, Charlotte, et al.
Publicado: (2023)

Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
por: Schwarz, Tatjana, et al.
Publicado: (2021)

Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study
por: Hillus, David, et al.
Publicado: (2021)

Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections
por: Tober-Lau, Pinkus, et al.
Publicado: (2022)

Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study
por: Thibeault, Charlotte, et al.
Publicado: (2021)

Neutralisation sensitivity of the SARS-CoV-2 omicron BA.2.75 sublineage
por: Gruell, Henning, et al.
Publicado: (2022)

mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant
por: Gruell, Henning, et al.
Publicado: (2022)

Immunogenicity of COVID-19 Tozinameran Vaccination in Patients on Chronic Dialysis
por: Schrezenmeier, Eva, et al.
Publicado: (2021)

Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescents
por: Steinbeis, Fridolin, et al.
Publicado: (2022)

Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial
por: Kurth, Florian, et al.
Publicado: (2023)

Pharmacokinetics of Nirmatrelvir and Ritonavir in COVID-19 Patients with End-Stage Renal Disease on Intermittent Hemodialysis
por: Lingscheid, Tilman, et al.
Publicado: (2022)

Severity of respiratory failure and computed chest tomography in acute COVID-19 correlates with pulmonary function and respiratory symptoms after infection with SARS-CoV-2: An observational longitudinal study over 12 months
por: Steinbeis, Fridolin, et al.
Publicado: (2022)

Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses
por: Schlickeiser, Stephan, et al.
Publicado: (2021)

Type of vaccine and immunosuppressive therapy but not diagnosis critically influence antibody response after COVID-19 vaccination in patients with rheumatic disease
por: Frommert, Leonie Maria, et al.
Publicado: (2022)

Post-treatment haemolysis is common following oral artemisinin combination therapy of uncomplicated malaria in travellers
por: Kurth, Florian, et al.
Publicado: (2023)

Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults
por: Vanshylla, Kanika, et al.
Publicado: (2022)

SARS-CoV-2 Proteome-Wide Analysis Revealed Significant Epitope Signatures in COVID-19 Patients
por: Schwarz, Tatjana, et al.
Publicado: (2021)

Monkeypox in-patients with severe anal pain
por: Pfäfflin, Frieder, et al.
Publicado: (2022)

SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns
por: Gruell, Henning, et al.
Publicado: (2022)

The human host response to monkeypox infection: a proteomic case series study
por: Wang, Ziyue, et al.
Publicado: (2022)

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence
por: Kostadinova, Elena, et al.
Publicado: (2016)

A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort study
por: Wang, Ziyue, et al.
Publicado: (2022)

Impaired B Cell Recall Memory and Reduced Antibody Avidity but Robust T Cell Response in CVID Patients After COVID-19 Vaccination
por: Steiner, Sophie, et al.
Publicado: (2023)

Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives
por: Müller-Redetzky, Holger C., et al.
Publicado: (2014)

Complement activation induces excessive T cell cytotoxicity in severe COVID-19
por: Georg, Philipp, et al.
Publicado: (2022)

CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity
por: Doehn, Jan-Moritz, et al.
Publicado: (2021)

Therapeutic strategies in pneumonia: going beyond antibiotics
por: Müller-Redetzky, Holger, et al.
Publicado: (2015)

Brain magnetic resonance imaging in imported malaria
por: Frölich, Andreas M., et al.
Publicado: (2019)

Estimating infectiousness throughout SARS-CoV-2 infection course
por: Jones, Terry C., et al.
Publicado: (2021)

Reactive T Cells in Convalescent COVID-19 Patients With Negative SARS-CoV-2 Antibody Serology
por: Steiner, Sophie, et al.
Publicado: (2021)

NOD-Like Receptors in Lung Diseases
por: Chaput, Catherine, et al.
Publicado: (2013)

Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination
por: Habermann, Elisa, et al.
Publicado: (2022)

Characterization of intrinsic and effective fitness changes caused by temporarily fixed mutations in the SARS-CoV-2 spike E484 epitope and identification of an epistatic precondition for the evolution of E484A in variant Omicron
por: Schröder, Simon, et al.
Publicado: (2023)

Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies
por: Akbil, Bengisu, et al.
Publicado: (2022)

Preserved T cell responses to SARS-CoV-2 in anti-CD20 treated multiple sclerosis
por: Schwarz, Tatjana, et al.
Publicado: (2022)

Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens
por: Wang, Zijun, et al.
Publicado: (2022)

Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection
por: Messner, Christoph B., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9k9e6b50s7p5q9orati9thconf