Proteomics and Transcriptomics of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Patients

OBJECTIVE: To identify the molecular signaling pathways underlying sudden unexpected death in epilepsy (SUDEP) and high-risk SUDEP compared to control patients with epilepsy. METHODS: For proteomics analyses, we evaluated the hippocampus and frontal cortex from microdissected postmortem brain tissue...

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Detalles Bibliográficos
Autores principales: Leitner, Dominique F., Mills, James D., Pires, Geoffrey, Faustin, Arline, Drummond, Eleanor, Kanshin, Evgeny, Nayak, Shruti, Askenazi, Manor, Verducci, Chloe, Chen, Bei Jun, Janitz, Michael, Anink, Jasper J., Baayen, Johannes C., Idema, Sander, van Vliet, Erwin A., Devore, Sasha, Friedman, Daniel, Diehl, Beate, Scott, Catherine, Thijs, Roland, Wisniewski, Thomas, Ueberheide, Beatrix, Thom, Maria, Aronica, Eleonora, Devinsky, Orrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205452/
https://www.ncbi.nlm.nih.gov/pubmed/33910938
http://dx.doi.org/10.1212/WNL.0000000000011999

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