Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ

We previously reported xanthohumol (XN), and its synthetic derivative tetrahydro-XN (TXN), attenuates high-fat diet (HFD)-induced obesity and metabolic syndrome in C57Bl/6J mice. The objective of the current study was to determine the effect of XN and TXN on lipid accumulation in the liver. Non-supp...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Bobe, Gerd, Miranda, Cristobal L, Lowry, Malcolm B, Hsu, Victor L, Lohr, Christiane V, Wong, Carmen P, Jump, Donald B, Robinson, Matthew M, Sharpton, Thomas J, Maier, Claudia S, Stevens, Jan F, Gombart, Adrian F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205491/
https://www.ncbi.nlm.nih.gov/pubmed/34128467
http://dx.doi.org/10.7554/eLife.66398

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