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Structural basis for the coiled-coil architecture of human CtIP
The DNA repair factor CtIP has a critical function in double-strand break (DSB) repair by homologous recombination, promoting the assembly of the repair apparatus at DNA ends and participating in DNA-end resection. However, the molecular mechanisms of CtIP function in DSB repair remain unclear. Here...
Autores principales: | Morton, C. R., Rzechorzek, N. J., Maman, J. D., Kuramochi, M., Sekiguchi, H., Rambo, R., Sasaki, Y. C., Davies, O. R., Pellegrini, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205527/ https://www.ncbi.nlm.nih.gov/pubmed/34129781 http://dx.doi.org/10.1098/rsob.210060 |
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