Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever

We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already dec...

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Detalles Bibliográficos
Autores principales: Buijs, Sheila B., Stuart, Sanne K., Oosterheert, Jan Jelrik, Karhof, Steffi, Hoepelman, Andy I. M., Renders, Nicole H. M., van Petersen, André S., Bleeker-Rovers, Chantal P., Wever, Peter C., Koning, Olivier H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205920/
https://www.ncbi.nlm.nih.gov/pubmed/33566203
http://dx.doi.org/10.1007/s10096-021-04179-5
Descripción
Sumario:We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already deceased or lost to follow-up. Of 107 patients, 25 (23.4%) became seronegative, 77 (72.0%) retained a profile of past resolved Q fever infection, and five (4.7%) developed chronic Q fever. We urge clinicians to stay vigilant for chronic Q fever beyond two years after primary infection and perform serological testing based on clinical presentation.

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