Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever

We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already dec...

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Autores principales: Buijs, Sheila B., Stuart, Sanne K., Oosterheert, Jan Jelrik, Karhof, Steffi, Hoepelman, Andy I. M., Renders, Nicole H. M., van Petersen, André S., Bleeker-Rovers, Chantal P., Wever, Peter C., Koning, Olivier H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205920/
https://www.ncbi.nlm.nih.gov/pubmed/33566203
http://dx.doi.org/10.1007/s10096-021-04179-5
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author Buijs, Sheila B.
Stuart, Sanne K.
Oosterheert, Jan Jelrik
Karhof, Steffi
Hoepelman, Andy I. M.
Renders, Nicole H. M.
van Petersen, André S.
Bleeker-Rovers, Chantal P.
Wever, Peter C.
Koning, Olivier H. J.
author_facet Buijs, Sheila B.
Stuart, Sanne K.
Oosterheert, Jan Jelrik
Karhof, Steffi
Hoepelman, Andy I. M.
Renders, Nicole H. M.
van Petersen, André S.
Bleeker-Rovers, Chantal P.
Wever, Peter C.
Koning, Olivier H. J.
author_sort Buijs, Sheila B.
collection PubMed
description We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already deceased or lost to follow-up. Of 107 patients, 25 (23.4%) became seronegative, 77 (72.0%) retained a profile of past resolved Q fever infection, and five (4.7%) developed chronic Q fever. We urge clinicians to stay vigilant for chronic Q fever beyond two years after primary infection and perform serological testing based on clinical presentation.
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spelling pubmed-82059202021-07-01 Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever Buijs, Sheila B. Stuart, Sanne K. Oosterheert, Jan Jelrik Karhof, Steffi Hoepelman, Andy I. M. Renders, Nicole H. M. van Petersen, André S. Bleeker-Rovers, Chantal P. Wever, Peter C. Koning, Olivier H. J. Eur J Clin Microbiol Infect Dis Brief Report We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already deceased or lost to follow-up. Of 107 patients, 25 (23.4%) became seronegative, 77 (72.0%) retained a profile of past resolved Q fever infection, and five (4.7%) developed chronic Q fever. We urge clinicians to stay vigilant for chronic Q fever beyond two years after primary infection and perform serological testing based on clinical presentation. Springer Berlin Heidelberg 2021-02-10 2021 /pmc/articles/PMC8205920/ /pubmed/33566203 http://dx.doi.org/10.1007/s10096-021-04179-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Report
Buijs, Sheila B.
Stuart, Sanne K.
Oosterheert, Jan Jelrik
Karhof, Steffi
Hoepelman, Andy I. M.
Renders, Nicole H. M.
van Petersen, André S.
Bleeker-Rovers, Chantal P.
Wever, Peter C.
Koning, Olivier H. J.
Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
title Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
title_full Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
title_fullStr Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
title_full_unstemmed Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
title_short Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
title_sort long-term serological follow-up after primary coxiella burnetii infection in patients with vascular risk factors for chronic q fever
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205920/
https://www.ncbi.nlm.nih.gov/pubmed/33566203
http://dx.doi.org/10.1007/s10096-021-04179-5
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