DNA methylation at birth potentially mediates the association between prenatal lead (Pb) exposure and infant neurodevelopmental outcomes

Early-life lead (Pb) exposure has been linked to adverse neurodevelopmental outcomes. Recent evidence has indicated a critical role of DNA methylation (DNAm) in cognition, and Pb exposure has also been shown to alter DNAm. However, it is unknown whether DNAm is part of the mechanism of Pb neurotoxic...

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Detalles Bibliográficos
Autores principales: Rygiel, Christine A, Dolinoy, Dana C, Bakulski, Kelly M, Aung, Max T, Perng, Wei, Jones, Tamara R, Solano-González, Maritsa, Hu, Howard, Tellez-Rojo, Martha M, Schnaas, Lourdes, Marcela, Erika, Peterson, Karen E, Goodrich, Jaclyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206046/
https://www.ncbi.nlm.nih.gov/pubmed/34141453
http://dx.doi.org/10.1093/eep/dvab005

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