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Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach

Otitis media, a common disease marked by the presence of fluid within the middle ear space, imparts a significant global health and economic burden. Identifying an effusion through the tympanic membrane is critical to diagnostic success but remains challenging due to the inherent limitations of visi...

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Autores principales: Kashani, Rustin G., Młyńczak, Marcel C., Zarabanda, David, Solis-Pazmino, Paola, Huland, David M., Ahmad, Iram N., Singh, Surya P., Valdez, Tulio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206083/
https://www.ncbi.nlm.nih.gov/pubmed/34131163
http://dx.doi.org/10.1038/s41598-021-91736-9
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author Kashani, Rustin G.
Młyńczak, Marcel C.
Zarabanda, David
Solis-Pazmino, Paola
Huland, David M.
Ahmad, Iram N.
Singh, Surya P.
Valdez, Tulio A.
author_facet Kashani, Rustin G.
Młyńczak, Marcel C.
Zarabanda, David
Solis-Pazmino, Paola
Huland, David M.
Ahmad, Iram N.
Singh, Surya P.
Valdez, Tulio A.
author_sort Kashani, Rustin G.
collection PubMed
description Otitis media, a common disease marked by the presence of fluid within the middle ear space, imparts a significant global health and economic burden. Identifying an effusion through the tympanic membrane is critical to diagnostic success but remains challenging due to the inherent limitations of visible light otoscopy and user interpretation. Here we describe a powerful diagnostic approach to otitis media utilizing advancements in otoscopy and machine learning. We developed an otoscope that visualizes middle ear structures and fluid in the shortwave infrared region, holding several advantages over traditional approaches. Images were captured in vivo and then processed by a novel machine learning based algorithm. The model predicts the presence of effusions with greater accuracy than current techniques, offering specificity and sensitivity over 90%. This platform has the potential to reduce costs and resources associated with otitis media, especially as improvements are made in shortwave imaging and machine learning.
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spelling pubmed-82060832021-06-16 Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach Kashani, Rustin G. Młyńczak, Marcel C. Zarabanda, David Solis-Pazmino, Paola Huland, David M. Ahmad, Iram N. Singh, Surya P. Valdez, Tulio A. Sci Rep Article Otitis media, a common disease marked by the presence of fluid within the middle ear space, imparts a significant global health and economic burden. Identifying an effusion through the tympanic membrane is critical to diagnostic success but remains challenging due to the inherent limitations of visible light otoscopy and user interpretation. Here we describe a powerful diagnostic approach to otitis media utilizing advancements in otoscopy and machine learning. We developed an otoscope that visualizes middle ear structures and fluid in the shortwave infrared region, holding several advantages over traditional approaches. Images were captured in vivo and then processed by a novel machine learning based algorithm. The model predicts the presence of effusions with greater accuracy than current techniques, offering specificity and sensitivity over 90%. This platform has the potential to reduce costs and resources associated with otitis media, especially as improvements are made in shortwave imaging and machine learning. Nature Publishing Group UK 2021-06-15 /pmc/articles/PMC8206083/ /pubmed/34131163 http://dx.doi.org/10.1038/s41598-021-91736-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kashani, Rustin G.
Młyńczak, Marcel C.
Zarabanda, David
Solis-Pazmino, Paola
Huland, David M.
Ahmad, Iram N.
Singh, Surya P.
Valdez, Tulio A.
Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
title Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
title_full Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
title_fullStr Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
title_full_unstemmed Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
title_short Shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
title_sort shortwave infrared otoscopy for diagnosis of middle ear effusions: a machine-learning-based approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206083/
https://www.ncbi.nlm.nih.gov/pubmed/34131163
http://dx.doi.org/10.1038/s41598-021-91736-9
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