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Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma

Glioma is one of the most lethal cancers with highly vascularized networks and growing evidences have identified glioma stem cells (GSCs) to account for excessive angiogenesis in glioma. Aberrant expression of paired-related homeobox1 (Prrx1) has been functionally associated with cancer stem cells i...

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Detalles Bibliográficos
Autores principales:	Chen, Zetao, Chen, Yihong, Li, Yan, Lian, Weidong, Zheng, Kehong, Zhang, Yuxuan, Zhang, Yujie, Lin, Chuang, Liu, Chaoqun, Sun, Fei, Sun, Xinlin, Wang, Jihui, Zhao, Liang, Ke, Yiquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206106/ https://www.ncbi.nlm.nih.gov/pubmed/34131109 http://dx.doi.org/10.1038/s41419-021-03882-7

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