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Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release

Human neutrophils constitutively express high amounts of arginase-1, which depletes arginine from the surrounding medium and downregulates T-cell activation. Here, we have found that neutrophil arginase-1, released from activated human neutrophils or dead cells, induced apoptosis in cancer cells thr...

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Detalles Bibliográficos
Autores principales:	García-Navas, Rósula, Gajate, Consuelo, Mollinedo, Faustino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206108/ https://www.ncbi.nlm.nih.gov/pubmed/34131176 http://dx.doi.org/10.1038/s41598-021-91947-0

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