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Acrolein contributes to human colorectal tumorigenesis through the activation of RAS-MAPK pathway

Colorectal cancer (CRC) is one of the most well-known malignancies with high prevalence and poor 5-year survival. Previous studies have demonstrated that a high-fat diet (HFD) is capable of increasing the odds of developing CRC. Acrolein, an IARC group 2A carcinogen, can be formed from carbohydrates...

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Detalles Bibliográficos
Autores principales:	Tsai, Hong-Chieh, Tsou, Han-Hsing, Lin, Chun-Chi, Chen, Shao-Chen, Cheng, Hsiao-Wei, Liu, Tsung-Yun, Chen, Wei-Shone, Jiang, Jeng-Kai, Yang, Shung-Haur, Chang, Shih-Ching, Teng, Hao-Wei, Wang, Hsiang-Tsui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206110/ https://www.ncbi.nlm.nih.gov/pubmed/34131238 http://dx.doi.org/10.1038/s41598-021-92035-z

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