Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

Current kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney’s collecting duct (CD) system. Here, we report the generation of an expandable, 3D branching ureteric bud (UB) organoid culture model that can be derived from primary UB pro...

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Detalles Bibliográficos
Autores principales: Zeng, Zipeng, Huang, Biao, Parvez, Riana K., Li, Yidan, Chen, Jyunhao, Vonk, Ariel C., Thornton, Matthew E., Patel, Tadrushi, Rutledge, Elisabeth A., Kim, Albert D., Yu, Jingying, Grubbs, Brendan H., McMahon, Jill A., Pastor-Soler, Nuria M., Hallows, Kenneth R., McMahon, Andrew P., Li, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206157/
https://www.ncbi.nlm.nih.gov/pubmed/34131121
http://dx.doi.org/10.1038/s41467-021-23911-5

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