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Quantifying the contribution of dominance deviation effects to complex trait variation in biobank-scale data
The proportion of variation in complex traits that can be attributed to non-additive genetic effects has been a topic of intense debate. The availability of biobank-scale datasets of genotype and trait data from unrelated individuals opens up the possibility of obtaining precise estimates of the con...
Autores principales: | Pazokitoroudi, Ali, Chiu, Alec M., Burch, Kathryn S., Pasaniuc, Bogdan, Sankararaman, Sriram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206203/ https://www.ncbi.nlm.nih.gov/pubmed/33811807 http://dx.doi.org/10.1016/j.ajhg.2021.03.018 |
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