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Fatty acids suppress the steroidogenesis of the MA-10 mouse Leydig cell line by downregulating CYP11A1 and inhibiting late-stage autophagy

Obese men have lower circulating testosterone than men with an optimal body mass index. Elevated fatty acids (FAs) caused by obesity have been reported to suppress the steroidogenesis of Leydig cells. Recent studies have demonstrated that autophagy regulates steroidogenesis in endocrine cells; howev...

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Detalles Bibliográficos
Autores principales:	Huang, Chien, Hsu, Hsiu-Ju, Wang, Mu-En, Hsu, Meng-Chieh, Wu, Leang-Shin, Jong, De-Shien, Jiang, Yi-Fan, Chiu, Chih-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206377/ https://www.ncbi.nlm.nih.gov/pubmed/34131222 http://dx.doi.org/10.1038/s41598-021-92008-2

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