Cargando…
Bispecific Antibody Molecule Inhibits Tumor Cell Proliferation More Efficiently Than the Two-Molecule Combination
BACKGROUND: Monoclonal antibodies (mAbs) have proved to be a valuable tool for the treatment of different cancer types. However, clinical use of an increasing number of mAbs, have also highlighted limitations with monotherapy for cancers, in particular for such with more complex mechanisms, requirin...
Autores principales: | Volk, Anna-Luisa, Mebrahtu, Aman, Ko, Bong-Kook, Lundqvist, Magnus, Karlander, Maximilian, Lee, Hyun-Jong, Frejd, Fredrik Y., Kim, Kyu-Tae, Lee, Jong-Seo, Rockberg, Johan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206453/ https://www.ncbi.nlm.nih.gov/pubmed/33721246 http://dx.doi.org/10.1007/s40268-021-00339-2 |
Ejemplares similares
-
A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation
por: Mega, Alessandro, et al.
Publicado: (2023) -
Affibody molecules as engineered protein drugs
por: Frejd, Fredrik Y, et al.
Publicado: (2017) -
Targeting HER3 using mono- and bispecific antibodies or alternative scaffolds
por: Malm, Magdalena, et al.
Publicado: (2016) -
Small Bispecific Affinity Proteins for Simultaneous
Target Binding and Albumin-Associated Half-Life Extension
por: von Witting, Emma, et al.
Publicado: (2020) -
Intercellular Adhesion Molecule 1: More than a Leukocyte Adhesion Molecule
por: Haydinger, Cameron D., et al.
Publicado: (2023)