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Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19

BACKGROUND AND OBJECTIVE: The COVID-19 coronavirus disease outbreak is evolving around the world. The aim of this study is to evaluate the association between influenza vaccination and the risk of mortality in hospitalized COVID-19 patients, as well as other risk factors. MATERIALS AND METHODS: Retr...

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Autores principales: Fernández Ibáñez, José Manuel, Morales Ballesteros, María del Carmen, Fernández Anguita, Manuel José, Galindo Andúgar, María Ángeles, Arias Arias, Ángel, Barberá-Farré, José Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206630/
https://www.ncbi.nlm.nih.gov/pubmed/34304882
http://dx.doi.org/10.1016/j.medcli.2021.06.003
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author Fernández Ibáñez, José Manuel
Morales Ballesteros, María del Carmen
Fernández Anguita, Manuel José
Galindo Andúgar, María Ángeles
Arias Arias, Ángel
Barberá-Farré, José Ramón
author_facet Fernández Ibáñez, José Manuel
Morales Ballesteros, María del Carmen
Fernández Anguita, Manuel José
Galindo Andúgar, María Ángeles
Arias Arias, Ángel
Barberá-Farré, José Ramón
author_sort Fernández Ibáñez, José Manuel
collection PubMed
description BACKGROUND AND OBJECTIVE: The COVID-19 coronavirus disease outbreak is evolving around the world. The aim of this study is to evaluate the association between influenza vaccination and the risk of mortality in hospitalized COVID-19 patients, as well as other risk factors. MATERIALS AND METHODS: Retrospective observational study. This study was conducted among hospitalized patients with COVID-19 at Hospital La Mancha Centro between March 5 and 25, 2020. Information on influenza vaccination was extracted from electronic medical records. We used a multivariate logistic regression to explore the association between influenza vaccination and mortality from COVID and other risk factors. RESULTS: 410 patients were included. Influenza vaccine had no effect among COVID-19 hospitalized patients [OR: 1.55 (95%CI: 0.96 – 2.48; p=0.071)]. Increasing hospital mortality was associated with older age [OR: 1.05 (95% CI 1.02–1.07), per year increase; p<0.001)], Charlson ≥3 [OR: 1.84 (95%CI: 1.07-3.15, p=0.027)] and heart failure on admission [OR: 6 (IC95%: 1.6 – 21.7; p=0.007)] CONCLUSIONS: Influenza vaccine had no effect among COVID-19 hospitalized patients. The risk factors identified were older age, higher comorbidity and heart failure on admission.
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spelling pubmed-82066302021-06-16 Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19 Fernández Ibáñez, José Manuel Morales Ballesteros, María del Carmen Fernández Anguita, Manuel José Galindo Andúgar, María Ángeles Arias Arias, Ángel Barberá-Farré, José Ramón Med Clin (Barc) Original Breve BACKGROUND AND OBJECTIVE: The COVID-19 coronavirus disease outbreak is evolving around the world. The aim of this study is to evaluate the association between influenza vaccination and the risk of mortality in hospitalized COVID-19 patients, as well as other risk factors. MATERIALS AND METHODS: Retrospective observational study. This study was conducted among hospitalized patients with COVID-19 at Hospital La Mancha Centro between March 5 and 25, 2020. Information on influenza vaccination was extracted from electronic medical records. We used a multivariate logistic regression to explore the association between influenza vaccination and mortality from COVID and other risk factors. RESULTS: 410 patients were included. Influenza vaccine had no effect among COVID-19 hospitalized patients [OR: 1.55 (95%CI: 0.96 – 2.48; p=0.071)]. Increasing hospital mortality was associated with older age [OR: 1.05 (95% CI 1.02–1.07), per year increase; p<0.001)], Charlson ≥3 [OR: 1.84 (95%CI: 1.07-3.15, p=0.027)] and heart failure on admission [OR: 6 (IC95%: 1.6 – 21.7; p=0.007)] CONCLUSIONS: Influenza vaccine had no effect among COVID-19 hospitalized patients. The risk factors identified were older age, higher comorbidity and heart failure on admission. Elsevier España, S.L.U. 2022-06-24 2021-06-16 /pmc/articles/PMC8206630/ /pubmed/34304882 http://dx.doi.org/10.1016/j.medcli.2021.06.003 Text en © 2021 Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Breve
Fernández Ibáñez, José Manuel
Morales Ballesteros, María del Carmen
Fernández Anguita, Manuel José
Galindo Andúgar, María Ángeles
Arias Arias, Ángel
Barberá-Farré, José Ramón
Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
title Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
title_full Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
title_fullStr Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
title_full_unstemmed Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
title_short Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
title_sort influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por covid-19
topic Original Breve
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206630/
https://www.ncbi.nlm.nih.gov/pubmed/34304882
http://dx.doi.org/10.1016/j.medcli.2021.06.003
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