Cargando…
Bacterial Protein Homeostasis Disruption as a Therapeutic Intervention
Cells have evolved a complex molecular network, collectively called the protein homeostasis (proteostasis) network, to produce and maintain proteins in the appropriate conformation, concentration and subcellular localization. Loss of proteostasis leads to a reduction in cell viability, which occurs...
Autores principales: | Khodaparast, Laleh, Wu, Guiqin, Khodaparast, Ladan, Schmidt, Béla Z., Rousseau, Frederic, Schymkowitz, Joost |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206779/ https://www.ncbi.nlm.nih.gov/pubmed/34150852 http://dx.doi.org/10.3389/fmolb.2021.681855 |
Ejemplares similares
-
Enhanced therapeutic window for antimicrobial Pept-ins by investigating their structure-activity relationship
por: Wu, Guiqin, et al.
Publicado: (2023) -
Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness
por: Mortier, Julien, et al.
Publicado: (2021) -
The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation
por: Dewachter, Liselot, et al.
Publicado: (2021) -
Erratum for Mortier and Gayán et al., “Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness”
por: Mortier, Julien, et al.
Publicado: (2021) -
Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based
Platform for In Vivo PET Imaging of Intracellular
Targets
por: Siemons, Maxime, et al.
Publicado: (2021)