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Platelet-Derived Growth Factor-D Activates Complement System to Propagate Macrophage Polarization and Neovascularization
Platelet-derived growth factor-D (PDGF-D) is highly expressed in immune cells. However, the potential role of PDGF-D in immune system remains thus far unclear. Here, we reveal a novel function of PDGF-D in activating both classical and alternative complement pathways that markedly increase chemokine...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207142/ https://www.ncbi.nlm.nih.gov/pubmed/34150781 http://dx.doi.org/10.3389/fcell.2021.686886 |