Cargando…

Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis

INTRODUCTION:  Several studies have shown an inconsistent relationship between postimplantation pocket hematoma and cardiac implantable electronic device (CIED) infection. In this study, we performed a systematic review and meta‐analysis to explore the effect of postimplantation hematoma and the ris...

Descripción completa

Detalles Bibliográficos
Autores principales: Kewcharoen, Jakrin, Kanitsoraphan, Chanavuth, Thangjui, Sittinun, Leesutipornchai, Thiratest, Saowapa, Sakditad, Pokawattana, Apichai, Navaravong, Leenhapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207394/
https://www.ncbi.nlm.nih.gov/pubmed/34141016
http://dx.doi.org/10.1002/joa3.12516
_version_ 1783708767856099328
author Kewcharoen, Jakrin
Kanitsoraphan, Chanavuth
Thangjui, Sittinun
Leesutipornchai, Thiratest
Saowapa, Sakditad
Pokawattana, Apichai
Navaravong, Leenhapong
author_facet Kewcharoen, Jakrin
Kanitsoraphan, Chanavuth
Thangjui, Sittinun
Leesutipornchai, Thiratest
Saowapa, Sakditad
Pokawattana, Apichai
Navaravong, Leenhapong
author_sort Kewcharoen, Jakrin
collection PubMed
description INTRODUCTION:  Several studies have shown an inconsistent relationship between postimplantation pocket hematoma and cardiac implantable electronic device (CIED) infection. In this study, we performed a systematic review and meta‐analysis to explore the effect of postimplantation hematoma and the risk of CIED infection. METHODS:  We searched the databases of MEDLINE and EMBASE from inception to March 2020. Included studies were cohort studies, case‐control studies, cross‐sectional studies, and randomized controlled trials that reported incidence of postimplantation pocket hematoma and CIED infection during the follow‐up period. CIED infection was defined as either a device‐related local or systemic infection. Data from each study were combined using the random effects, generic inverse variance method of Der Simonian and Laird to calculate odds ratios (OR) and 95% confidence intervals (CI). RESULTS: Fourteen studies were included in final analysis, involving a total of 28 319 participants. In random‐effect model, we found that postimplantation pocket hematoma significantly increases the risk of overall CIED infection (OR = 6.30, 95% CI: 3.87‐10.24, I (2) = 49.3%). There was no publication bias observed in the funnel plot as well as no small‐study effect observed in Egger’s test. CONCLUSIONS: Our meta‐analysis demonstrated that postimplantation pocket hematoma significantly increases the risk of CIED infection. Precaution should be taken during device implantation to reduce postimplantation hematoma and subsequent CIED infection.
format Online
Article
Text
id pubmed-8207394
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-82073942021-06-16 Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis Kewcharoen, Jakrin Kanitsoraphan, Chanavuth Thangjui, Sittinun Leesutipornchai, Thiratest Saowapa, Sakditad Pokawattana, Apichai Navaravong, Leenhapong J Arrhythm Original Articles INTRODUCTION:  Several studies have shown an inconsistent relationship between postimplantation pocket hematoma and cardiac implantable electronic device (CIED) infection. In this study, we performed a systematic review and meta‐analysis to explore the effect of postimplantation hematoma and the risk of CIED infection. METHODS:  We searched the databases of MEDLINE and EMBASE from inception to March 2020. Included studies were cohort studies, case‐control studies, cross‐sectional studies, and randomized controlled trials that reported incidence of postimplantation pocket hematoma and CIED infection during the follow‐up period. CIED infection was defined as either a device‐related local or systemic infection. Data from each study were combined using the random effects, generic inverse variance method of Der Simonian and Laird to calculate odds ratios (OR) and 95% confidence intervals (CI). RESULTS: Fourteen studies were included in final analysis, involving a total of 28 319 participants. In random‐effect model, we found that postimplantation pocket hematoma significantly increases the risk of overall CIED infection (OR = 6.30, 95% CI: 3.87‐10.24, I (2) = 49.3%). There was no publication bias observed in the funnel plot as well as no small‐study effect observed in Egger’s test. CONCLUSIONS: Our meta‐analysis demonstrated that postimplantation pocket hematoma significantly increases the risk of CIED infection. Precaution should be taken during device implantation to reduce postimplantation hematoma and subsequent CIED infection. John Wiley and Sons Inc. 2021-03-13 /pmc/articles/PMC8207394/ /pubmed/34141016 http://dx.doi.org/10.1002/joa3.12516 Text en © 2021 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Kewcharoen, Jakrin
Kanitsoraphan, Chanavuth
Thangjui, Sittinun
Leesutipornchai, Thiratest
Saowapa, Sakditad
Pokawattana, Apichai
Navaravong, Leenhapong
Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis
title Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis
title_full Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis
title_fullStr Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis
title_full_unstemmed Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis
title_short Postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: A meta‐analysis
title_sort postimplantation pocket hematoma increases risk of cardiac implantable electronic device infection: a meta‐analysis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207394/
https://www.ncbi.nlm.nih.gov/pubmed/34141016
http://dx.doi.org/10.1002/joa3.12516
work_keys_str_mv AT kewcharoenjakrin postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis
AT kanitsoraphanchanavuth postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis
AT thangjuisittinun postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis
AT leesutipornchaithiratest postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis
AT saowapasakditad postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis
AT pokawattanaapichai postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis
AT navaravongleenhapong postimplantationpockethematomaincreasesriskofcardiacimplantableelectronicdeviceinfectionametaanalysis