Cargando…

Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments

BACKGROUND: In-hospital mortality and short-term mortality are indicators that are commonly used to evaluate the outcome of emergency department (ED) treatment. Although several scoring systems and machine learning-based approaches have been suggested to grade the severity of the condition of ED pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Jinwoo, Lee, Sung Woo, Kim, Won Young, Han, Kap Su, Kim, Su Jin, Kang, Hyungoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207577/
https://www.ncbi.nlm.nih.gov/pubmed/34134648
http://dx.doi.org/10.1186/s12873-021-00466-8
_version_ 1783708799544066048
author Jeong, Jinwoo
Lee, Sung Woo
Kim, Won Young
Han, Kap Su
Kim, Su Jin
Kang, Hyungoo
author_facet Jeong, Jinwoo
Lee, Sung Woo
Kim, Won Young
Han, Kap Su
Kim, Su Jin
Kang, Hyungoo
author_sort Jeong, Jinwoo
collection PubMed
description BACKGROUND: In-hospital mortality and short-term mortality are indicators that are commonly used to evaluate the outcome of emergency department (ED) treatment. Although several scoring systems and machine learning-based approaches have been suggested to grade the severity of the condition of ED patients, methods for comparing severity-adjusted mortality in general ED patients between different systems have yet to be developed. The aim of the present study was to develop a scoring system to predict mortality in ED patients using data collected at the initial evaluation and to validate the usefulness of the scoring system for comparing severity-adjusted mortality between institutions with different severity distributions. METHODS: The study was based on the registry of the National Emergency Department Information System, which is maintained by the National Emergency Medical Center of the Republic of Korea. Data from 2016 were used to construct the prediction model, and data from 2017 were used for validation. Logistic regression was used to build the mortality prediction model. Receiver operating characteristic curves were used to evaluate the performance of the prediction model. We calculated the standardized W statistic and its 95% confidence intervals using the newly developed mortality prediction model. RESULTS: The area under the receiver operating characteristic curve of the developed scoring system for the prediction of mortality was 0.883 (95% confidence interval [CI]: 0.882–0.884). The Ws score calculated from the 2016 dataset was 0.000 (95% CI: − 0.021 – 0.021). The Ws score calculated from the 2017 dataset was 0.049 (95% CI: 0.030–0.069). CONCLUSIONS: The scoring system developed in the present study utilizing the parameters gathered in initial ED evaluations has acceptable performance for the prediction of in-hospital mortality. Standardized W statistics based on this scoring system can be used to compare the performance of an ED with the reference data or with the performance of other institutions.
format Online
Article
Text
id pubmed-8207577
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-82075772021-06-16 Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments Jeong, Jinwoo Lee, Sung Woo Kim, Won Young Han, Kap Su Kim, Su Jin Kang, Hyungoo BMC Emerg Med Research Article BACKGROUND: In-hospital mortality and short-term mortality are indicators that are commonly used to evaluate the outcome of emergency department (ED) treatment. Although several scoring systems and machine learning-based approaches have been suggested to grade the severity of the condition of ED patients, methods for comparing severity-adjusted mortality in general ED patients between different systems have yet to be developed. The aim of the present study was to develop a scoring system to predict mortality in ED patients using data collected at the initial evaluation and to validate the usefulness of the scoring system for comparing severity-adjusted mortality between institutions with different severity distributions. METHODS: The study was based on the registry of the National Emergency Department Information System, which is maintained by the National Emergency Medical Center of the Republic of Korea. Data from 2016 were used to construct the prediction model, and data from 2017 were used for validation. Logistic regression was used to build the mortality prediction model. Receiver operating characteristic curves were used to evaluate the performance of the prediction model. We calculated the standardized W statistic and its 95% confidence intervals using the newly developed mortality prediction model. RESULTS: The area under the receiver operating characteristic curve of the developed scoring system for the prediction of mortality was 0.883 (95% confidence interval [CI]: 0.882–0.884). The Ws score calculated from the 2016 dataset was 0.000 (95% CI: − 0.021 – 0.021). The Ws score calculated from the 2017 dataset was 0.049 (95% CI: 0.030–0.069). CONCLUSIONS: The scoring system developed in the present study utilizing the parameters gathered in initial ED evaluations has acceptable performance for the prediction of in-hospital mortality. Standardized W statistics based on this scoring system can be used to compare the performance of an ED with the reference data or with the performance of other institutions. BioMed Central 2021-06-16 /pmc/articles/PMC8207577/ /pubmed/34134648 http://dx.doi.org/10.1186/s12873-021-00466-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Jeong, Jinwoo
Lee, Sung Woo
Kim, Won Young
Han, Kap Su
Kim, Su Jin
Kang, Hyungoo
Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments
title Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments
title_full Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments
title_fullStr Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments
title_full_unstemmed Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments
title_short Development and validation of a scoring system for mortality prediction and application of standardized W statistics to assess the performance of emergency departments
title_sort development and validation of a scoring system for mortality prediction and application of standardized w statistics to assess the performance of emergency departments
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207577/
https://www.ncbi.nlm.nih.gov/pubmed/34134648
http://dx.doi.org/10.1186/s12873-021-00466-8
work_keys_str_mv AT jeongjinwoo developmentandvalidationofascoringsystemformortalitypredictionandapplicationofstandardizedwstatisticstoassesstheperformanceofemergencydepartments
AT leesungwoo developmentandvalidationofascoringsystemformortalitypredictionandapplicationofstandardizedwstatisticstoassesstheperformanceofemergencydepartments
AT kimwonyoung developmentandvalidationofascoringsystemformortalitypredictionandapplicationofstandardizedwstatisticstoassesstheperformanceofemergencydepartments
AT hankapsu developmentandvalidationofascoringsystemformortalitypredictionandapplicationofstandardizedwstatisticstoassesstheperformanceofemergencydepartments
AT kimsujin developmentandvalidationofascoringsystemformortalitypredictionandapplicationofstandardizedwstatisticstoassesstheperformanceofemergencydepartments
AT kanghyungoo developmentandvalidationofascoringsystemformortalitypredictionandapplicationofstandardizedwstatisticstoassesstheperformanceofemergencydepartments