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MSC-derived small extracellular vesicles overexpressing miR-20a promoted the osteointegration of porous titanium alloy by enhancing osteogenesis via targeting BAMBI

BACKGROUND: Patients with osteoporosis have a high risk of implant loosening due to poor osteointegration, possibly leading to implant failure, implant revision, and refracture. RNA interference therapy is an emerging epigenetic treatment, and we found that miR-20a could enhance osteogenesis. Moreov...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Huang, Jinghuan, Chen, Feng, Xie, Dong, Wang, Longqing, Ye, Cheng, Zhu, Qi, Li, Xiang, Li, Xiaolin, Yang, Lili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207591/ https://www.ncbi.nlm.nih.gov/pubmed/34134765 http://dx.doi.org/10.1186/s13287-021-02303-y

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