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Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides

Etheno (and ethano) derivatives of nucleic acid bases have an extra 5-membered ring attached. These were first noted as wyosine bases in tRNAs. Some were fluorescent, and the development of etheno derivatives of adenosine, cytosine, and guanosine led to the synthesis of fluorescent analogs of ATP, N...

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Detalles Bibliográficos
Autores principales: Guengerich, F. Peter, Ghodke, Pratibha P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207595/
https://www.ncbi.nlm.nih.gov/pubmed/34130743
http://dx.doi.org/10.1186/s41021-021-00199-x