Cargando…
Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides
Etheno (and ethano) derivatives of nucleic acid bases have an extra 5-membered ring attached. These were first noted as wyosine bases in tRNAs. Some were fluorescent, and the development of etheno derivatives of adenosine, cytosine, and guanosine led to the synthesis of fluorescent analogs of ATP, N...
Autores principales: | Guengerich, F. Peter, Ghodke, Pratibha P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207595/ https://www.ncbi.nlm.nih.gov/pubmed/34130743 http://dx.doi.org/10.1186/s41021-021-00199-x |
Ejemplares similares
-
Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N(2)-ethenodeoxyguanosine by human DNA translesion polymerase η
por: Ghodke, Pratibha P., et al.
Publicado: (2021) -
Oxidation and Glycolytic Cleavage of Etheno and Propano DNA Base Adducts†
por: Knutson, Charles G., et al.
Publicado: (2009) -
Ultrasensitive UPLC-MS-MS Method for the Quantitation of Etheno-DNA Adducts in Human Urine
por: Cui, Shiwei, et al.
Publicado: (2014) -
DNA Damage in Rheumatoid Arthritis: An Age-Dependent Increase in the Lipid Peroxidation-Derived DNA Adduct, Heptanone-Etheno-2′-Deoxycytidine
por: Ogawa, Masako, et al.
Publicado: (2013) -
The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts
por: Linhart, Kirsten, et al.
Publicado: (2014)