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The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures

OBJECTIVES: To investigate the role of a preoperative modified frailty index (mFI) based on data from medical records in predicting postoperative complications among older Chinese patients with hip fractures. METHODS: This retrospective cohort study included consecutive older patients with hip fract...

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Autores principales: Shen, Yanjiao, Hao, Qiukui, Wang, Yuting, Chen, Xiaoyan, Jiang, Jiaojiao, Dong, Birong, Guyatt, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207648/
https://www.ncbi.nlm.nih.gov/pubmed/34134662
http://dx.doi.org/10.1186/s12877-021-02330-7
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author Shen, Yanjiao
Hao, Qiukui
Wang, Yuting
Chen, Xiaoyan
Jiang, Jiaojiao
Dong, Birong
Guyatt, Gordon
author_facet Shen, Yanjiao
Hao, Qiukui
Wang, Yuting
Chen, Xiaoyan
Jiang, Jiaojiao
Dong, Birong
Guyatt, Gordon
author_sort Shen, Yanjiao
collection PubMed
description OBJECTIVES: To investigate the role of a preoperative modified frailty index (mFI) based on data from medical records in predicting postoperative complications among older Chinese patients with hip fractures. METHODS: This retrospective cohort study included consecutive older patients with hip fracture admitted to the Department of Orthopaedics, West China Hospital, Sichuan University, from December 2010 to June 2017 who underwent surgical repair. We selected 33 variables, including characteristics of hip fracture, to construct a mFI. Each variable was coded with a value of 0 when a deficit was absent or 1 when it was present. We calculated the mFI as the proportion of positive items and defined frailty as mFI value greater than or equal to 0.21 according to threshold proposed by Hoover et al. We examined the relationship between mFI and severity of postoperative complications and the occurrence of in-hospital pneumonia including statistical adjustment for several demographics (e.g. age, gender, and marital status) and habits (smoking and alcohol intake), time from fracture to surgery in the multivariable model. RESULTS: We included 965 patients (34% male; mean age: 76.77 years; range: 60 to 100 years) with a prevalence of frailty of 13.06%. The presence of frailty was associated with a higher severity of complications (OR: 2.07; 95% CI: 1.40 to 3.05). Frail patients were more likely to develop in-hospital pneumonia than non-frail patients (OR: 2.08; 95% CI: 1.28 to 3.39). CONCLUSION: The preoperative modified frailty index based on data from medical records proved significantly associated with postoperative complications among older patients with hip fractures undergoing hip surgery. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02330-7.
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spelling pubmed-82076482021-06-16 The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures Shen, Yanjiao Hao, Qiukui Wang, Yuting Chen, Xiaoyan Jiang, Jiaojiao Dong, Birong Guyatt, Gordon BMC Geriatr Research OBJECTIVES: To investigate the role of a preoperative modified frailty index (mFI) based on data from medical records in predicting postoperative complications among older Chinese patients with hip fractures. METHODS: This retrospective cohort study included consecutive older patients with hip fracture admitted to the Department of Orthopaedics, West China Hospital, Sichuan University, from December 2010 to June 2017 who underwent surgical repair. We selected 33 variables, including characteristics of hip fracture, to construct a mFI. Each variable was coded with a value of 0 when a deficit was absent or 1 when it was present. We calculated the mFI as the proportion of positive items and defined frailty as mFI value greater than or equal to 0.21 according to threshold proposed by Hoover et al. We examined the relationship between mFI and severity of postoperative complications and the occurrence of in-hospital pneumonia including statistical adjustment for several demographics (e.g. age, gender, and marital status) and habits (smoking and alcohol intake), time from fracture to surgery in the multivariable model. RESULTS: We included 965 patients (34% male; mean age: 76.77 years; range: 60 to 100 years) with a prevalence of frailty of 13.06%. The presence of frailty was associated with a higher severity of complications (OR: 2.07; 95% CI: 1.40 to 3.05). Frail patients were more likely to develop in-hospital pneumonia than non-frail patients (OR: 2.08; 95% CI: 1.28 to 3.39). CONCLUSION: The preoperative modified frailty index based on data from medical records proved significantly associated with postoperative complications among older patients with hip fractures undergoing hip surgery. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02330-7. BioMed Central 2021-06-16 /pmc/articles/PMC8207648/ /pubmed/34134662 http://dx.doi.org/10.1186/s12877-021-02330-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Shen, Yanjiao
Hao, Qiukui
Wang, Yuting
Chen, Xiaoyan
Jiang, Jiaojiao
Dong, Birong
Guyatt, Gordon
The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures
title The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures
title_full The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures
title_fullStr The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures
title_full_unstemmed The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures
title_short The association between preoperative modified frailty index and postoperative complications in Chinese elderly patients with hip fractures
title_sort association between preoperative modified frailty index and postoperative complications in chinese elderly patients with hip fractures
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207648/
https://www.ncbi.nlm.nih.gov/pubmed/34134662
http://dx.doi.org/10.1186/s12877-021-02330-7
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