Cargando…

Early detection of myocardial changes with and without dexrazoxane using serial magnetic resonance imaging in a pre-clinical mouse model

BACKGROUND: Cancer therapy-related cardiac dysfunction may occur in pediatric cancer survivors. Identification of early markers of myocardial damage secondary to anthracycline exposure is crucial to develop strategies that may ameliorate this complication. OBJECTIVES: The purpose of this study was t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Noel, Cory V., Rainusso, Nino, Robertson, Matthew, Romero, Jonathan, Masand, Prakash, Coarfa, Cristian, Pautler, Robia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207719/ https://www.ncbi.nlm.nih.gov/pubmed/34134789 http://dx.doi.org/10.1186/s40959-021-00109-8

Ejemplares similares

Anthracycline extravasation injuries: management with dexrazoxane
por: Jordan, Karin, et al.
Publicado: (2009)

Scavenging Effects of Dexrazoxane on Free Radicals
por: Junjing, Zhang, et al.
Publicado: (2010)

Dexrazoxane Shows No Protective Effect in the Acute Phase of Reperfusion during Myocardial Infarction in Pigs
por: Kamat, Pranitha, et al.
Publicado: (2016)

Dexrazoxane for the treatment of chemotherapy-related side effects
por: Langer, Seppo W
Publicado: (2014)

MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma
por: Nirala, Bikesh K., et al.
Publicado: (2023)

Dexrazoxane for Preventing Anthracycline Cardiotoxicity in Children with Solid Tumors
por: Choi, Hyoung Soo, et al.
Publicado: (2010)

Dexrazoxane for cardioprotection in older adults with acute myeloid leukemia
por: Vachhani, Pankit, et al.
Publicado: (2017)

Cisplatin/dexrazoxane/doxorubicin: Neutropenia and thrombocytopenia: case report
Publicado: (2020)

Efficacy of Dexrazoxane in Preventing Anthracycline Cardiotoxicity in Breast Cancer
por: Macedo, Ariane V.S., et al.
Publicado: (2019)

Fluorinated Eu(II)-based multimodal contrast agent for temperature- and redox-responsive magnetic resonance imaging
por: Basal, Lina A., et al.
Publicado: (2017)

Development and Validation of New RP-HPLC Method for the Determination of Dexrazoxane
por: Basaveswara Rao, M. V., et al.
Publicado: (2012)

Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma
por: Narayan, Hari K, et al.
Publicado: (2019)

Efficacy of Dexrazoxane in Cardiac Protection in Pediatric Patients Treated With Anthracyclines
por: Rahimi, Parya, et al.
Publicado: (2023)

Detection of subclinical cardiotoxicity in sarcoma patients receiving continuous doxorubicin infusion or pre-treatment with dexrazoxane before bolus doxorubicin
por: Li, Jieli, et al.
Publicado: (2020)

Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane
por: Maloney, S L, et al.
Publicado: (2009)

Dexrazoxane ameliorates radiation-induced heart disease in a rat model
por: Li, Long, et al.
Publicado: (2021)

Dexrazoxane does not mitigate early vascular toxicity induced by doxorubicin in mice
por: Bosman, Matthias, et al.
Publicado: (2023)

Effect of Dexrazoxane and Amifostine on the Vertebral Bone Quality of Doxorubicin Treated Male Rats
por: Mwale, F, et al.
Publicado: (2008)

Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study
por: QuanJun, Yang, et al.
Publicado: (2017)

Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)

Risk Factor Analysis for Secondary Malignancy in Dexrazoxane-Treated Pediatric Cancer Patients
por: Kim, Hyery, et al.
Publicado: (2019)

A Simulation Workshop for Pediatric Residents Using Team-Based Reflective Practice to Communicate Life-Altering News
por: Rainusso, Nino, et al.
Publicado: (2022)

Consensus-Based Cardiomyopathy Care in Childhood Cancer Survivors: When You Don’t Have a Roadmap, Ask Directions
por: Ryan, Thomas D., et al.
Publicado: (2022)

Mitochondrial superoxide: a key player in Alzheimer's disease
por: Massaad, Cynthia A., et al.
Publicado: (2009)

Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562
por: Sargent, J M, et al.
Publicado: (2001)

Correction: Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)

Dynamic Trend of Myocardial Edema in Takotsubo Syndrome: A Serial Cardiac Magnetic Resonance Study
por: Kato, Ken, et al.
Publicado: (2022)

TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke
por: Cao, Zhijuan, et al.
Publicado: (2017)

Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice
por: Kropp, Jenna, et al.
Publicado: (2015)

The Lack of Synergy between Carvedilol and the Preventive Effect of Dexrazoxane in the Model of Chronic Anthracycline-Induced Cardiomyopathy
por: Szponar, Jaroslaw, et al.
Publicado: (2023)

Assessment of the relationships between myocardial contractility and infarct tissue revealed by serial magnetic resonance imaging in patients with acute myocardial infarction
por: McComb, Christie, et al.
Publicado: (2015)

Myocardial remodeling and susceptibility to ventricular tachycardia in a model of chronic epilepsy
por: Lai, Yi‐Chen, et al.
Publicado: (2018)

Pharmocologic treatment with histone deacetylase 6 inhibitor (ACY-738) recovers Alzheimer's disease phenotype in amyloid precursor protein/presenilin 1 (APP/PS1) mice
por: Majid, Tabassum, et al.
Publicado: (2015)

Dexrazoxane may prevent doxorubicin-induced DNA damage via depleting both Topoisomerase II isoforms
por: Deng, Shiwei, et al.
Publicado: (2014)

Dexrazoxane improves cardiac autonomic function in epirubicin-treated breast cancer patients with type 2 diabetes
por: Sun, Fangyi, et al.
Publicado: (2016)

Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
por: Yu, Xiaoxue, et al.
Publicado: (2020)

Upfront dexrazoxane for the reduction of anthracycline-induced cardiotoxicity in adults with preexisting cardiomyopathy and cancer: a consecutive case series
por: Ganatra, Sarju, et al.
Publicado: (2019)

In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization
por: Mody, Hardik, et al.
Publicado: (2023)

A Mouse Holder for Awake Functional Imaging in Unanesthetized Mice: Applications in (31)P Spectroscopy, Manganese-Enhanced Magnetic Resonance Imaging Studies, and Resting-State Functional Magnetic Resonance Imaging
por: Fadel, Lindsay C., et al.
Publicado: (2022)

Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
por: Popelová, O, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_kecrv93g882lt37stubh71uuq8