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Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report
BACKGROUND: Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon. CASE PRESENTATION: This report describes a case with CVT, w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207742/ https://www.ncbi.nlm.nih.gov/pubmed/34134639 http://dx.doi.org/10.1186/s12883-021-02261-1 |
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author | Wen, Hongfeng Jin, Di Chen, Yu Cui, Bin Xiao, Tianyi |
author_facet | Wen, Hongfeng Jin, Di Chen, Yu Cui, Bin Xiao, Tianyi |
author_sort | Wen, Hongfeng |
collection | PubMed |
description | BACKGROUND: Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon. CASE PRESENTATION: This report describes a case with CVT, which is manifested as space-occupying lesions of the cerebellar hemisphere and mimics a cerebellar tumor at the beginning. The diagnosis of CVT was finalized given the laboratory and brain biopsy findings. The etiology may be related to polycythemia vera with Janus Kinase 2 V617F mutation. CONCLUSION: Isolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected. Polycythemia vera, especially with a positive JAK2 V617F mutation, may be a rare risk factor for CVT. |
format | Online Article Text |
id | pubmed-8207742 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82077422021-06-16 Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report Wen, Hongfeng Jin, Di Chen, Yu Cui, Bin Xiao, Tianyi BMC Neurol Case Report BACKGROUND: Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon. CASE PRESENTATION: This report describes a case with CVT, which is manifested as space-occupying lesions of the cerebellar hemisphere and mimics a cerebellar tumor at the beginning. The diagnosis of CVT was finalized given the laboratory and brain biopsy findings. The etiology may be related to polycythemia vera with Janus Kinase 2 V617F mutation. CONCLUSION: Isolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected. Polycythemia vera, especially with a positive JAK2 V617F mutation, may be a rare risk factor for CVT. BioMed Central 2021-06-16 /pmc/articles/PMC8207742/ /pubmed/34134639 http://dx.doi.org/10.1186/s12883-021-02261-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Wen, Hongfeng Jin, Di Chen, Yu Cui, Bin Xiao, Tianyi Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
title | Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
title_full | Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
title_fullStr | Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
title_full_unstemmed | Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
title_short | Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
title_sort | cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207742/ https://www.ncbi.nlm.nih.gov/pubmed/34134639 http://dx.doi.org/10.1186/s12883-021-02261-1 |
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