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Ensemble switching unveils a kinetic rheostat mechanism of the eukaryotic thiamine pyrophosphate riboswitch

Thiamine pyrophosphate (TPP) riboswitches regulate thiamine metabolism by inhibiting the translation of enzymes essential to thiamine synthesis pathways upon binding to thiamine pyrophosphate in cells across all domains of life. Recent work on the Arabidopsis thaliana TPP riboswitch suggests a multi...

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Detalles Bibliográficos
Autores principales:	Ma, Junyan, Saikia, Nabanita, Godar, Subash, Hamilton, George L., Ding, Feng, Alper, Joshua, Sanabria, Hugo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208051/ https://www.ncbi.nlm.nih.gov/pubmed/33863818 http://dx.doi.org/10.1261/rna.075937.120

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