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GABPα and CREB1 Binding to Double Nucleotide Polymorphisms of Their Consensus Motifs and Cooperative Binding to the Composite ETS ⇔ CRE Motif (ACCGGAAGTGACGTCA)

[Image: see text] Previously, cooperative binding of the bZIP domain of CREB1 and the ETS domain of GABPα was observed for the composite DNA ETS ⇔ CRE motif (A(0)C(1)C(2)G(3)G(4)A(5)A(6)G(7)T(8)G(9)A(10)C(11)G(12)T(13)C(14)A(15)). Single nucleotide polymorphisms (SNPs) at the beginning and end of th...

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Detalles Bibliográficos
Autores principales: Assad, Nima, Tillo, Desiree, Ray, Sreejana, Dzienny, Alexa, FitzGerald, Peter C., Vinson, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208074/
https://www.ncbi.nlm.nih.gov/pubmed/34151054
http://dx.doi.org/10.1021/acsomega.9b00540

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